Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact, made up of a network of strands to act as a molecular gasket for preventing the leakage of ions, water etc., between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different claudin composition.
A synthetic peptide corresponding to C-terminal of human claudin 1.
cell membrane, Cytoplasmic
|Positive Control Tissue
Breast carcinoma, skin
Citrate Buffer pH 6.0
|Incubation & Temperature
30 min @ RT
PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System
Rabbit Polyclonal Antibody
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