Description
This antibody reacts with a 145 kDa protein. CD117/c-kit is a transmembrane receptor tyrosine kinase and is expressed in many tissues and cells. CD117/ckit is involved in the development of several lineages of stem cells, such as germ cells, neural crest derived melanocytes and hematopoietic precursor cells. This antibody can be used in the identification of gastrointestinal stromaltumors.
Additional information
| Catalog No. | PDR045, PDR045-HL, RP063, RP063-05 |
|---|---|
| Clone | Rabbit |
| Isotype | _ |
| Immunogen | A synthetic peptide from C-terminus of human CD117/c-kit protein. |
| Species | Mouse |
| Cellular Localization | cell membrane, Cytoplasmic |
| Positive Control Tissue | Tonsil |
| Pretreatment | EDTA Buffer pH 8.0 (Manual/ Montage) |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD, RUO |
| Detection System | PolyVue™ Plus – Two Step Detection System or Montage PolyVue Plus™ Auto Detection System for Montage 360 System or HighLighter core kit for HighLighter Staining System |
| Description/Type | RTU Rabbit Polyclonal Antibody |
| Format | Purified immunoglobulin |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Arber et al. Hum Pathol 29: 498, 1998.
- Rajpert et al. J Pathol 178: 166, 1996
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