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Home / Primary Antibodies / IVD - Outside U.S. Market
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Formalin fixed paraffin embedded human kidney stained with CD34 antibody.

CD34, Endothelial Cell

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Catalog No: 8637 Categories: Primary Antibodies, IVD - For U.S. Market, IVD - Outside U.S. Market Tags: HL72K-Core Kit, Concentrated, C, Highlighter Product
PRODUCT CATEGORIES
  • Primary Antibodies
    • IVD - For U.S. Market
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    • RUO - Outside U.S. Market
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Description

This antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Anti-CD34 labels more than 85% of angiosarcoma and Kaposi’s sarcoma, but with a lower specificity.

Additional information
Clone

QBEND/10

Isotype

IgG1, kappa

Immunogen

Detergent solubilized vesicular suspension prepared from human term placenta.

Species

Mouse

Cellular Localization

cell membrane

Positive Control Tissue

Kidney, Tonsil

Pretreatment

Citrate Buffer pH 6.0 (Manual/ Montage)

Incubation & Temperature

30 min @ RT

Intended Use

IVD

Detection System

PolyVue™ Plus – Two Step Detection System or Montage PolyVue Plus™ Auto Detection System for Montage 360 System or HighLighter core kit for HighLighter Staining System

Description/Type

Mouse Monoclonal Antibody

Format

Purified immunoglobulin

DATASHEETS & SDS

DATASHEETS & SDS

Download Datasheet
Download SDS Sheet – OSHA

Download SDS Sheet – EU

REFERENCES

REFERENCES

  • Frolova, Let al., Monoclonal antibody IC0-115 to human CD34 antigen. Herald of the Cancer Research Center of RAMS. Sapp!, p. 10-12, 1994.
  • Miettinen M, et aLGastrointestinal stromal tumors of the stomach: a dinicopathologic, immunohistochemical, and molecular genetic study of 1765 cases with long-term follow-up. Am.( Sorg Pothol. 2005 lan;29 (1):52-68.
  • Ryan P, et al. Human herpesvirus 8 (HHV-8) detected in two patients with Kaposi’s sarcoma-like pyagenk granuloma. J Oin hallo!. 2002 Aug;SS (8):619-22.
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