TAG-72 /CA 72-4 (B72.3)

Name: TAG-72 /CA 72-4 (B72.3) – Mob288 – DBS
SKU: Mob288-
Availability: InStock

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Catalog No: Mob288- Categories: Primary Antibodies, IVD - For U.S. Market, IVD - Outside U.S. Market Tags: Highlighter Product, HL72K-Core Kit, Concentrated, T

Description

This antibody recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This antibody defined the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP15 is valuable in the diagnosis of apocrine carcinoma.

Additional information

Catalog No.	Mob288 Concentrated, PDM100 Prediluted
Clone	B72.3
Isotype	IgG1, kappa
Immunogen	Membrane enriched fraction of a human breast carcinoma liver metastasis.
Species	Mouse
Cellular Localization	cell surface, Cytoplasmic
Positive Control Tissue	Colon carcinoma
Pretreatment	Citrate Buffer pH 6.0
Incubation & Temperature	30 min @ RT
Intended Use	IVD
Detection System	PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System
Description/Type	Mouse Monoclonal Antibody
Format	This product is supplied as a tissue culture supernatant and contains sodium azide as a preservative.