Description
This antibody is specific to an 85 kDa protein known as XRCC1. X-ray repair cross complementing 1 (XRCC1) protein plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the Cterminal 96 amino acids and to DNA polymerase β through the N-terminal half. In testis XRCC1 is expressed at high levels.
Additional information
| Catalog No. | Mob325, Mob325R – Concentrated |
|---|---|
| Clone | 33-2-5 |
| Isotype | IgG2b |
| Immunogen | BALB/C mice were injected with recombinant human XRCC1 protein. |
| Species | Mouse |
| Cellular Localization | Nuclear |
| Positive Control Tissue | Testis |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD, RUO |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Conc Mouse Monoclonal Antibody |
| Format | Purified immunoglobulin |
DATASHEETS & SDS
REFERENCES
REFERENCES
- Labudova et al. Pediatric Res 41: 435, 1997.
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