Testicular Cancer Awareness Month! 2025

April is Testicular Cancer Awareness Month!

We are committed to support early detection through precise cancer marker identification. Our reagents help pathologists diagnose and research testicular cancer, ensuring better patient outcomes.

Shedding light on the key markers:

OCT3/4: A marker that can identify almost all seminoma and embryonal carcinoma, however, is negative in Yolk sac tumor, teratoma, sertoli-leydig cell tumor and lymhomas. It helps pathologist in making definite diagnose and staging testicular cancer.

SALL4: Highly expressed in nearly all non-trophoblastic germ cell tumors, such as seminoma, embryonal carcinoma, yolk sac tumor, and germ cell neoplasia in situ. It should be recognized that this marker is also expressed in malignant rhabdoid tumor, Wilms tumor, acute myeloid leukemia, diffuse large B cell lymphoma and hepatocellular carcinoma.

PLAP (Placental Alkaline Phosphatase): A marker found in seminomas (100%) with strong diffuse membranous and cytoplasmic staining positivity, very useful in distinquishing seminoma from spermatocytic tumor. However, it is frequently in low intensity focally expressed in embryonal carcinoma and yolk sac tumor. It helps pathologists confirm tumor types and monitor treatment progress.

Together, these markers improve the precision of diagnosis, enabling better outcomes through accurate detection and targeted treatment.

Let’s raise awareness and highlight the importance of accurate detection.