Description
This antibody recognizes a c-erbB-2 protein, which is a receptor tyrosine kinase of the c-erbB family. It is closely related in structure to the epidermal growth factor receptor. c-erbB-2 oncoprotein is detectable in a subset of breast and other adenocarcinomas, as well astransitional cell carcinomas. In the case of breast cancer, expression determined byimmunohistochemistry has been shown to be associated with poor prognosis.
Additional information
| Clone | SP3 |
|---|---|
| Isotype | Rabbit IgG |
| Immunogen | Recombinant protein encoding extracellular domain of human c-erbB2. |
| Species | Rabbit |
| Cellular Localization | cell membrane |
| Positive Control Tissue | Breast carcinoma |
| Pretreatment | Citrate Buffer pH 6.0 (Manual/ Montage) |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD, RUO |
| Detection System | PolyVue™ Plus – Two Step Detection System or Montage PolyVue Plus™ Auto Detection System for Montage 360 System or HighLighter core kit for HighLighter Staining System |
| Description/Type | Rabbit Monoclonal Antibody |
| Format | This product is supplied as a tissue culture supernatant and contains sodium azide as a preservative. |
DATASHEETS & SDS
REFERENCES
REFERENCES
- Kiernan, 1981: Sheehan & Hrapchak, 1980
Reviews (0)
Only logged in customers who have purchased this product may leave a review.
Reviews
There are no reviews yet.