Description
Multiple isoelectric variants of calponin have been identified but only two molecular weight isoforms exist (34kDa and 29kDa). Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
Additional information
| Catalog No. | Mob345 Concentrated, PDM219 Prediluted |
|---|---|
| Clone | CALP |
| Isotype | IgG1 |
| Immunogen | BALB/C mice were injected with crude human uterus extract. |
| Species | Mouse |
| Cellular Localization | Cytoplasmic |
| Positive Control Tissue | Uterus |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as a purified immunoglobulin and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
Frid et al. Dev Biol 153: 185, 1992.
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