Description
This antibody is specific to human prostatic acid phosphatase (PSAP), which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and secreted by the epithelial cells of the prostate gland. Prostatic acid phosphatase is a clinically important protein for its relevance as a biomarker of prostate carcinoma. Furthermore, it has a potential role in fertilization. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas.
Additional information
| Catalog No. | Mob085 Concentrated, PDM037 Prediluted |
|---|---|
| Clone | PASE/4LJ |
| Isotype | IgG1, kappa |
| Immunogen | Prostatic acid phosphatase purified from human seminal plasma. |
| Species | Mouse |
| Cellular Localization | Cytoplasmic |
| Positive Control Tissue | Prostate carcinoma |
| Pretreatment | EDTA Buffer pH 8.0 (Manual/ Montage) |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue™ Plus – Two Step Detection System or Montage PolyVue Plus™ Auto Detection System for Montage 360 System or HighLighter core kit for HighLighter Staining System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | Purified immunoglobulin |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Haines et al. Biochem Soc Trans 15: 1179, 1987.
- Haines et al. Br. J Cancer 60: 887, 1989.
- Li et al. Cancer 46: 1788, 1980.
- Hassan MI, et al., Structural and functional analysis of human
prostatic acid phosphatase. Expert Rev Anticancer Ther. 10(7): 1055-
68 (2010).
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