Description
This antibody reacts with β-amyloid protein. This antibody stains amyloid plaques within the cortex, and amyloid deposits in blood vessels. β-amyloid deposits are also detected in Lewy body dementia, Down syndrome, amyloidosis and in Gram-Parkinson dementia complex. The presence of a large number of neuritic plaques (senile) and neurofibrillary tangles in the cerebral cortex is used as a pathological marker for a disease state and presents the major criterion for the diagnosis of Alzheimer’s disease at autopsy.
Additional information
| Catalog No. | Mob410, Mob410-05 |
|---|---|
| Clone | BAM-10 |
| Isotype | IgG1 |
| Immunogen | A synthetic β-amyloid peptide (1-40) conjugated to KLH. |
| Species | Mouse |
| Cellular Localization | Cytoplasmic |
| Positive Control Tissue | Amyloidosis, Brain |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue™ Plus – Two Step Detection System or Montage PolyVue Plus™ Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as an ascites fluid. It contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Kang et al. Nature 325: 733, 1987.
- Tanzi et al. Nature 331: 528, 1988.
- Weidemann et al. Cell 57: 115, 1989.
- Yanker et al. Science 245: 417, 1989.
Reviews (0)
Only logged in customers who have purchased this product may leave a review.
Reviews
There are no reviews yet.