Description
The Bcl-2 product is considered to act as an inhibitor of apoptosis. Bcl-2 expression is inhibited in germinal centers where apoptosis forms part of the B cell production pathway. Reactive follicles show no staining for Bcl-2, whereas the cell in neoplastic follicles exhibit membrane staining. Bcl-2 α oncoprotein has been shown to inhibit apoptosis.
Additional information
| Catalog No. | Mob130 Concentrated, PDM209 Prediluted |
|---|---|
| Clone | 100/D5 |
| Isotype | IgG1 |
| Immunogen | BALB/C mice were injected with synthetic bcl-2 peptide. |
| Species | Mouse |
| Cellular Localization | Membranes |
| Positive Control Tissue | Tonsil |
| Pretreatment | EDTA Buffer pH 8.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | Tissue Culture Supernatant |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Hockenbery et al. Nature 348:334,1990
- LeBrun et al. Amer J Pathol 140:1327,1992
- Liu et al. Europ J Immunol 21:1905,1991
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