Description
Cadherin 17 is exclusively expressed in the epithelial cells of embryonic and adult small intestine, colon, liver, and pancreatic ducts. It has been reported to be frequently expressed in adenocarcinomas arising in the gastrointestinal tract and pancreas. Owing to its restricted expression in these groups of tumors, cadherin 17 has proven to be a useful immunohistochemical marker for assisting in distinguishing these neoplasms from other malignancies with which they may be confused
Additional information
| Catalog No. | Mob604R Concentrated, PDM604R Prediluted |
|---|---|
| Clone | 1H3 |
| Isotype | IgG1, kappa |
| Immunogen | Recombinant human cadherin 17 protein fragment (aa 24 -aa131) |
| Species | Mouse |
| Cellular Localization | Membranous and cytoplasmic |
| Positive Control Tissue | Colorectal Carcinoma and normal colon |
| Pretreatment | Tris EDTA Buffer pH9.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | RUO |
| Detection System | PolyVue Plus – Two Step Detection System Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | Purified immunoglobulin |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
I. Berndorff, D, et al. J Cell Biol 1994 ;125 :1353.
II. Panarelli, NC, et al. Am J Clin Pathol 2012 ;138 :211.
III. Lin, F, et al. Arch Pathol Lab Med 2014;138:1015
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