Description
Caspase 1 and is expressed as a proenzyme in many tissues. Active Caspase 1 is a tetramer of two subunits p10 and p20 in 2:2 ratio. Overexpression of caspase 1 can induce apoptosis in fibroblast, which can be inhibited by overexpression of Crm A, a protein from pox virus.
Additional information
| Catalog No. | PDR175, PDR175R – Prediluted, RP175, RP175R – Concentrated |
|---|---|
| Clone | Rabbit |
| Immunogen | Caspase1 (1-250aa) protein |
| Species | Rabbit |
| Cellular Localization | cell membrane, Nuclear |
| Positive Control Tissue | Placenta |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD, RUO |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Rabbit Polyclonal Antibody |
| Format | Purified immunoglobulin fraction ofrabbit antiserum against human Caspase 1 containing sodium azide as a preservative. |
DATASHEETS & SDS
REFERENCES
REFERENCES
- Enari et al. Nature 375: 78, 1995.
- Walker et al. Cell 78: 343, 1994.
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