Description
CD138, also known as Syndecan-1, is a member of the transmembrane heparan sulfate proteoglycan family, acts as an extracellular matrix receptor and is involved in many cellular functions, including cell-cell adhesion and cell-matrix adhesion. CD138 expression is found in both hematopoietic and non-hematopoietic cells. In the hematopoietic system, CD138 labels plasma cells. It is an excellent marker for plasmacytic differentiation within the spectrum of hematologic malignancy. Among non-hematolymphoid cells, CD138 reactivity is observed in many types of epithelial cells and stoma cells in both normal and tumor tissues.
Additional information
| Catalog No. | Mob588 Concentrated, PDM588 Prediluted |
|---|---|
| Clone | B-A38 |
| Isotype | IgG1 |
| Immunogen | U266 cell line |
| Species | Mouse |
| Cellular Localization | Membrane |
| Positive Control Tissue | Tonsil |
| Pretreatment | EDTA Buffer pH 8.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360/HighLighter System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | Purified immunoglobulin |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Elenius K, et al.: J Biol Chem1990, 265:17837-17843
- MaliM, et al.: J Biol Chem1990, 265:6884-6889
- O’Connell FP, et al.: AmJ Clin Pathol 2004, 121:254-263
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