CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This antibody can be used for immnophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues.
CD20, B-cell (L26)
Catalog No: 8283
Categories: IVD - For U.S. Market, Primary Antibodies, IVD - Outside U.S. Market
Tags: Concentrated, C, Highlighter Product, HL72K-Core Kit
Description
Additional information
Clone | L26 |
---|---|
Isotype | IgG2a, kappa |
Immunogen | BALB/C mice were injected with human tonsil B cells. |
Species | Mouse |
Cellular Localization | cell membrane, Cytoplasmic |
Positive Control Tissue | Tonsil |
Pretreatment | Citrate Buffer pH 6.0 (Manual/ Montage) |
Incubation & Temperature | 30 min @ RT |
Intended Use | IVD |
Detection System | PolyVue™ Plus – Two Step Detection System or Montage PolyVue Plus™ Auto Detection System for Montage 360 System or HighLighter core kit for HighLighter Staining System |
Description/Type | Mouse Monoclonal Antibody |
Format | This product is supplied as a cell culture supernatant and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
Download Datasheet |
Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Ishii et al. Clin Exp Immunol 58: 183, 1984.
- Mason et al. Am J Pathol 136: 1215, 1990.
- Cartun et al. Am J Pathol 129: 415, 1987.
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