Description
This antibody recognizes CD5, which is a transmembrane protein, is found on 95%of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Occasionally, CD5 antigen is also expressed on a subset of B cells. Mantle cell lymphomas(same as diffuse centrocytic lymphomas) are CD5(+) while the follicle center cell lymphoma are CD5(-).
Additional information
| Clone | SP19 |
|---|---|
| Isotype | Rabbit IgG |
| Immunogen | Synthetic peptide from the intracellular region of CD5. |
| Species | Rabbit |
| Cellular Localization | cell membrane |
| Positive Control Tissue | Tonsil |
| Pretreatment | EDTA Buffer pH 8.0 |
| Incubation & Temperature | 30-60 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Rabbit Monoclonal Antibody |
| Format | This product is supplied as a tissue culture supernatant and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Chan JK, et al., A proposal for classification of lymphoid neoplasms (by the
International Lymphoma Study Group). Histopathology 1994; 25:517-36. - Kasaian MT, et al. CD5 + B lymphocytes. Proc Soc Exp Bio and Med. 1991;
197:226-4.1
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