Description
This antibody reacts with a 65 kDa protein known as Cdc25A. The activity of cyclin-dependent kinases in cell cycle is regulated by the phosphorylation status, which is controlled by the antagonistic action of wee 1 kinase and Cdc25 phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B and CDC25C. Cdc25A and Cdc25B are expressed throughout the cell cycle, with peak expression in G1 for Cdc25A and in both G1-S phase and G2 for Cdc25B. Cdc25C is mainly expressed in G2 phase.
Additional information
| Catalog No. | Mob337, Mob337-05 |
|---|---|
| Clone | DCS-120 |
| Isotype | IgG2a |
| Immunogen | BALB/C mice were injected with purified recombinant Cdc25A. |
| Species | Mouse |
| Cellular Localization | Nuclear membrane |
| Positive Control Tissue | Tonsil |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as a purified immunoglobulin and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Draetta et at J Biochem Biophys Acta 1332 (2): 53, 1997.
- Gabrielli et at Oncogene 15 (7): 749, 1997.
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