Description
This antibody recognizes Chromogranin A. Chromogranin A (a protein of 439 amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.
Additional information
| Clone | LK2H10 |
|---|---|
| Isotype | IgG1, kappa |
| Immunogen | BALB/C mice were immunized with human pheochromocytoma. |
| Species | Mouse |
| Cellular Localization | Cytoplasmic |
| Positive Control Tissue | Pancreas, Small intestine |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as a purified immunoglobulin and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Bruke et al. Am J Surg Pathol 13: 828, 1989.
- Delagi et al. Mol Cell Probe 3: 87, 1989.
- Lloyd et al. Am J Pathol 130: 296, 1988.
- Weiler et al. Am J Surg Pathol 12: 877, 1988.
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