This antibody reacts with a protein of 60 kDa. E2Fs are DNAbinding proteins, which associate with negative regulators, such as the retinoblastoma p107 protein, resulting in an altered rate of gene transcription. E2F-1 is proposed to be involved in several cellular processes that range from tumor suppression, cell progression and oncogenesis. E2F-1 over expression can also drive cells into apoptosis.
BALB/C mice were immunized with a recombinant human E2F-1 protein.
|Positive Control Tissue
Breast carcinoma, Tonsil
EDTA Buffer pH 8.0
|Incubation & Temperature
30 min @ RT
PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System
Mouse Monoclonal Antibody
This product is supplied as an ascites fluid. It contains sodium azide as a preservative.
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