Description
This antibody reacts with a 33-36 kDa protein known as ERCC1 (excision repair cross complementing) polypeptide. ERCC1 is required for nucleotide excision repair of damaged DNA and is homologous to RAD10. In mammalian cells, XPG cleaves 3’ of the DNA lesion while ERCC1-XPF complex makes the 5’ incision.
Additional information
| Clone | 8F1 |
|---|---|
| Isotype | IgG2b |
| Immunogen | BALB/C mice were injected with full length recombinant human ERCC1 protein. |
| Species | Mouse |
| Cellular Localization | Nuclear |
| Positive Control Tissue | Tonsil |
| Pretreatment | EDTA Buffer pH8.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as a purified immunoglobulin and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- i)Hayashi et al.Mutat Res 407: 269, 1996.
- ii)Miura et al. Exp cell Rec 226: 126, 1996
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