Description
This antibody reacts with a protein of 81 kDa. Ezrin serves as a tyrosine kinase substrate and is phosphorylated in EGF-stimulated cells. Ezrin is a cytoplasmic protein, enriched in microvilli and other cell surfaces. Ezrin has an actin-binding capacity. Ezrin is expressed in epithelial cells but not in mesenchymal cells. Ezrin is also expressed by certain epithelial tumors, such as renal cell adenocarcinomas.
Additional information
| Clone | 3C12 |
|---|---|
| Isotype | IgG1 |
| Immunogen | BALB/C mice were immunized with a recombinant fragment of human ezrin corresponding to amino acid 362-585. |
| Species | Mouse |
| Cellular Localization | cell membrane |
| Positive Control Tissue | Lung |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as an ascites fluid. It contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Bolding et at. Am 1 Pathol 148: 367,1996.
- Helander et al. Nature 382: 265, 1996.
- Turunen at al. 1 cell Bid 126:1445,1994.
Reviews (0)
Only logged in customers who have purchased this product may leave a review.
Reviews
There are no reviews yet.