Description
Laminins are a family of heterotrimeric extracellular glycoproteins consisting of alpha, beta, and gamma chains. Laminins mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin is expressed in heart, lung, kidney, muscle, pancreas, retina, and placenta. Very little or no expression is observed in brain and liver.
Additional information
| Clone | 4C7 |
|---|---|
| Isotype | IgG2a, kappa |
| Immunogen | The A chain of human laminin. |
| Species | Mouse |
| Cellular Localization | Basement membrane |
| Positive Control Tissue | Renal Cell Carcinoma, skin |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as a purified immunoglobulin and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA
|
REFERENCES
REFERENCES
- Autio-Ha irnainen et al. Lab Invest 64: 483, 1991.
- Engval et al. Cell Regulation 1: 731, 1990.
- Kleinman et al. Proc Natl Arad Sci USA 85: 1282, 1988.
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