This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. Mast cells contain a number of preformed chemicals mediators such as histamine, chymase, carboxypeptidase, and proteolytic tryptase. Human mast cell chymase is considered to be an important marker of mast cells and is an important mediator of inflammation.
Mast Cell Chymase
Catalog No: 8463
Categories: Primary Antibodies, IVD - For U.S. Market, IVD - Outside U.S. Market
Tags: M, Concentrated
Description
Additional information
Clone | CC1 |
---|---|
Isotype | IgG1 |
Immunogen | BALB/C mice were injected with a purified human skin chymase. |
Species | Mouse |
Cellular Localization | Cytoplasmic |
Positive Control Tissue | Tonsil |
Pretreatment | Citrate Buffer pH 6.0 |
Incubation & Temperature | 30 min @ RT |
Intended Use | IVD |
Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
Description/Type | Mouse Monoclonal Antibody |
Format | Purified immunoglobulin |
DATASHEETS & SDS
DATASHEETS & SDS
Download Datasheet |
Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Buckley et al. J Pathol 189: 138, 1999.
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