Description
This antibody reacts with a neuraminidase sensitive oligosaccharide side chain of a glycoconjugate present in immature melanosomes. It reacts with junctional and blue nevus cells. Non-melanocytic cells are negative.
Additional information
| Clone | HMB45 |
|---|---|
| Isotype | IgG1, kappa |
| Immunogen | BALB/C mice were injected with extract of pigmented melanoma metastases from lymph nodes. |
| Species | Mouse |
| Cellular Localization | Cytoplasmic |
| Positive Control Tissue | Melanoma |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as a tissue culture supernatant and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Gown et al. Am 1 Pathol 123: 195, 1986.
- Kapur et al. J Histochem Cytochem 40: 207, 1992.
- Leong et al. Su rg Pathol 2: 137, 1989.
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