Description
This antibody is specific to a 55 kDa protein known as platelet-derived endothelial growth factor (PD-ECGF), or thymidine phosphorylase (TP). High levels of TP/PD-ECGF are observed in cancer patients. High intracellular levels of TP/PD-ECGF are associated with increased sensitivity to fluoropyrimidine chemotherapeutic agents.
Additional information
| Catalog No. | Mob292 Concentrated |
|---|---|
| Clone | P-GF.44C |
| Isotype | IgG1 |
| Immunogen | BALB/C mice were injected with a recombinant full length human thymidine phosphorylase (TP/PD-ECGF) protein. |
| Species | Mouse |
| Cellular Localization | Cytoplasmic, Nuclear |
| Positive Control Tissue | Breast carcinoma, Thyroid |
| Pretreatment | EDTA Buffer pH 8.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as a purified immunoglobulin and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Fox SB, et al. Journal of Pathology, 1995, 176:183-90
- O’Brien TS, et al. Cancer Research, 1996, 56 (20): 4799-804
- Fox SB, et.al. British Journal of Cancer, 1996, 73:275-80
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