Uroplakin 3B is expressed on the surface of urothelial epithelial and mesothelial. Its antibody is very useful in identifying urothelial and mesothelial origin of cancers by immunohistochemistry. This protein encoded by this gene is a member of transmembrane 4 superfamily. The protein mediate signal transduction events that play a role in the regulation of cell development, activation.
Uroplakin 3B
Catalog No: RMAB117R-
Categories: Primary Antibodies, RUO - For U.S. Market, RUO - Outside U.S. Market
Description
Additional information
Catalog No. | RMAB117R, RMPD117R |
---|---|
Clone | DBRRM3.66 |
Isotype | IgG, kappa |
Immunogen | Recombinant human Uroplakin 3B protein fragment (around aa 100-300) |
Species | Rabbit |
Cellular Localization | Membranous |
Positive Control Tissue | Bladder |
Pretreatment | EDTA Buffer pH 8.0 (Manual/ Montage) |
Incubation & Temperature | 30 min @ RT |
Intended Use | RUO |
Detection System | PolyVue™ Plus – Two Step Detection System or Montage PolyVue Plus™ Auto Detection System for Montage 360 System or HighLighter core kit for HighLighter Staining System |
Description/Type | FFPE, Rabbit Monoclonal Antibody |
Format | Purified immunoglobulin |
DATASHEETS & SDS
DATASHEETS & SDS
Download Datasheet |
REFERENCES
REFERENCES
- i) Mod Pathol 2021;34:710
- ii) Hum Pathol 2022;125:97
- iii) Hum Pathol 2023;138:62
- iv) Int J Cancer Biomed Res 2023;7:13
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