Description
This MAb recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50, 48, 46, 45, and 40kDa. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Additional information
| Clone | AE1 |
|---|---|
| Isotype | IgG1, kappa |
| Immunogen | BALB/C mice were immunized with human epidermal keratin. |
| Species | Mouse |
| Cellular Localization | Cytoplasmic |
| Positive Control Tissue | Squamous Lung Carcinoma |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue™ Plus – Two Step Detection System or Montage PolyVue Plus™ Auto Detection System for Montage 360 System or HighLighter core kit for HighLighter Staining System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as a Protein G purified monoclonal antibody from CL1000 in vitro production and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Woodcock et al. ,J Cell Biol 95: 580, 1982.
- Tseng et al., Cell 30: 361, 1982.
- Sun et al., J Invest Dermatol 81: 109s, 1983.
- Spagnolo et al., Am J Clin pathol 84: 697, 1985.
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