Description
Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.
Additional information
| Clone | JC159 |
|---|---|
| Isotype | IgG1, kappa |
| Immunogen | Tissue Culture Harvest/Supernatant |
| Species | Mouse |
| Cellular Localization | cell membrane |
| Positive Control Tissue | Placenta, Tonsil |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue™ Plus – Two Step Detection System or Montage PolyVue Plus™ Auto Detection System for Montage 360 System or HighLighter core kit for HighLighter Staining System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as a tissue culture supernatant and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Andersson, L.C., et al. 1979. Glycophorin A as a cell surface marker of early
erythroid differentiation in acute leukemia. Int. J. Cancer 23: 717-720. - Liszka, K., et al., 1983. Glycophorin A expression in malignant hematopoiesis.
Am. J. Hematol. 15: 219-226.
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