Description
This antibody reacts with a 32-34 kDa protein known as replication protein A (RPA). RPA is involved in DNA replication, repair and recombination. Human RPA is a stable heterotrimer of 70 kDa, 32-34 kDa and 11-14 kDa subunits (RPA70, RPA32 and RPA14 respectively). RPA is required for the SV40 large tumor antigen-catalyzed unwinding for SV40 DNA and stimulates DNA polymerase α and δ.
Additional information
| Catalog No. | Mob329 Concentrated |
|---|---|
| Clone | 9H8 |
| Isotype | IgG1, kappa |
| Immunogen | BALB/C mice were injected with purified human RPA protein. |
| Species | Mouse |
| Cellular Localization | Nuclear |
| Positive Control Tissue | Tonsil |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Conc Mouse Monoclonal Antibody |
| Format | This product is supplied as a purified immunoglobulin and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Kenny et al. J Biol Chem 265 (13), 7693, 1990.
- Niu et al. J Biol Chem 272 (19): 12634, 1997.
- Pan et al. Proc Natl Acad Sci USA 92: 4636, 1995.
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