This antibody is specific to a cluster of proteins between 70-80 kDa known as tyrosinase. This antibody does not show any cross-reaction with MAGE-1 and tyrosinase-related protein-1, TRP-1/gp75. Staining of melanomas with this antibody showed tyrosinase in melanotic as well as amelanotic variants.
Tyrosinase, Melanoma Marker
Catalog No: Mob290-
Categories: Primary Antibodies, IVD - For U.S. Market, IVD - Outside U.S. Market
Tags: HL72K Plus-Core Plus Kit, Concentrated, T, Highlighter Product
Description
Additional information
| Catalog No. | Mob290 Concentrated, PDM150 Prediluted |
|---|---|
| Clone | T311 |
| Isotype | IgG2a |
| Immunogen | BALB/C mice were injected with a recombinant tyrosinase protein. |
| Species | Mouse |
| Cellular Localization | Cytoplasmic |
| Positive Control Tissue | Melanoma |
| Pretreatment | EDTA Buffer pH 8.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as a purified immunoglobulin and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Chen et al. Proc Natl Acad Sci USA 92: 8125, 1995.
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