Description
This antibody reacts with the c-erbB-2 oncoprotein, a 190 kDa protein. The proto-oncogene for c-erbB-2 islocated on the human chromosome 17, band 21. It has structural similarities to EGFR. Several studies have indicated that c-erbB-2 may be a good indicator of the prognosis of human carcinomas in the breast, ovary, uterus and gastrointestinal tract.
Additional information
| Clone | Rabbit |
|---|---|
| Isotype | _ |
| Immunogen | Keyhole limpet hemocyanin conjugated synthetic human peptide from c-erbB-2 oncoprotein. |
| Species | Rabbit |
| Cellular Localization | cell membrane |
| Positive Control Tissue | Breast carcinoma |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD, RUO |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Rabbit Polyclonal Antibody |
| Format | Affinity purified rabbit antiserum against human c-erbB-2 oncoprotein containing azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- i) Fukushige et al. Mol Cell Biol 6: 955, 1986.
- ii) Schechter et al. Science 229: 976, 1985.
- iii) Wright et al. Cancer Res 49: 2087, 1989.
- iv) Haerslev et al. Applied Immunohistochemistry 1: 223, 1993.
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