This antibody recognizes calcitonin, which is a 32 amino acid peptide, which can be demonstrated in C cells of the normal and hyperplastic thyroid. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.
Calcitonin (SP17)
Catalog No: RMAB009-
Categories: IVD - For U.S. Market, Primary Antibodies, IVD - Outside U.S. Market
Tags: Concentrated, C
Description
Additional information
Catalog No. | RMAB009 Concentrated, RMPD009 Prediluted |
---|---|
Clone | SP17 |
Isotype | IgG |
Immunogen | Synthetic human calcitonin 1-32 amino acid peptide. |
Species | Rabbit |
Cellular Localization | Cytoplasmic |
Positive Control Tissue | Thyroid or medullary carcinoma |
Pretreatment | Citrate Buffer pH 6.0 |
Incubation & Temperature | 30-60 min @ RT |
Intended Use | IVD |
Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
Description/Type | Rabbit Monoclonal Antibody |
Format | This product is supplied as a immunoglobulin and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
Download Datasheet |
Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
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