Description
This antibody is specific to high molecular weight (120-150 kDa) h-caldesmon. Caldesmon is involved in smooth muscle and non-muscle contraction. Two closely related variants of human caldesmon have been identified. The hcaldesmon variant is predominantly expressed in smooth muscle, whereas lcaldesmon (71-80 kD) is found in non-muscle tissue and cells.
Additional information
| Catalog No. | Mob556 Concentrated, PDM223 Prediluted |
|---|---|
| Clone | hHCD |
| Isotype | IgG1 |
| Immunogen | BALB/C mice were injected with human uterus smooth muscle extract. |
| Species | Mouse |
| Cellular Localization | Cytoplasmic |
| Positive Control Tissue | Endometrial cancer |
| Pretreatment | EDTA Buffer pH 8.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as a purified immunoglobulin and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Frid et al. Dev Biol 153, 185, (1992).
- Sobue K and Sellers JR J Biol Chem 266 (19): 12115, (1991).
- Ueki, N., et al., Proc. Natl. Acad. Sci USA, 84, 9049, (1987).
- Glukhova, M.A., et al., Proc. Natl. Acad. Sci. USA. 85, 9542,
(1988).
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