Multiple isoelectric variants of calponin have been identified but only two molecular weight isoforms exist (34kDa and 29kDa). Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
Mob345 Concentrated, PDM219 Prediluted
BALB/C mice were injected with crude human uterus extract.
|Positive Control Tissue
Citrate Buffer pH 6.0
|Incubation & Temperature
30 min @ RT
PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System
Mouse Monoclonal Antibody
This product is supplied as a purified immunoglobulin and contains sodium azide as a preservative.
Frid et al. Dev Biol 153: 185, 1992.
Only logged in customers who have purchased this product may leave a review.