Description
This antibody reacts with a 220kDa protein. CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. In is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 is very useful in identification of Hodgkin’s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes.
Additional information
| Clone | MMA |
|---|---|
| Isotype | IgM, kappa |
| Immunogen | BALB/C mice were injected with U937 histiocytic cell line. |
| Species | Mouse |
| Cellular Localization | cell membrane |
| Positive Control Tissue | Hodgkin’s |
| Pretreatment | EDTA Buffer pH 8.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as a tissue culture supernatant and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Hanjan et al. Clin Immuno Immunopathol 23:172, 1982.
- Hsu et al. Amer J Clin Pathol 82:29, 1984.
- Pinkus et al. Am J Pathol 119:244, 1985.
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