Cyclin D1 or PRAD-1 or bcl-1 is one of the key cell cycle regulators, and functions in association with cdk4 and/or cdk6 by phosphorylating the Rb protein. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms including mantle cell lymphomas (MCL).
Cyclin D1 (SP4)
Catalog No: 8685
Categories: Primary Antibodies, IVD - For U.S. Market, IVD - Outside U.S. Market
Tags: Concentrated, C
Description
Additional information
Catalog No. | RMAB003, RMPD003 |
---|---|
Clone | SP4 |
Isotype | Rabbit IgG |
Immunogen | A synthetic peptide from C-terminus of human cyclin D1. |
Species | Rabbit |
Cellular Localization | Nuclear |
Positive Control Tissue | Breast carcinoma |
Pretreatment | EDTA Buffer pH 8.0 |
Incubation & Temperature | 30 min @ RT |
Intended Use | IVD |
Detection System | PolyVue Plus – Two Step Detection System Montage PolyVue Plus Auto Detection Systemrnfor Montage 360 System |
Description/Type | Conc Rabbit Monoclonal Antibody |
Format | Purified immunoglobulin |
DATASHEETS & SDS
DATASHEETS & SDS
Download Datasheet |
Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
Cheuk et al. Am J Surg Path 28: 801, 2004.
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