Description
Anti-Cytokeratin (CAM 5.2) reagent has a primary reactivity with human keratin proteins that correspond to Moll’s peptides #7 and #8, Mr 48 and 52 kilodaltons (kd), respectively. Cytokeratin 7 and 8 are present on secretory epithelia of normal human tissue but not onstratified squamous epithelium. Anti-Cytokeratin (CAM 5.2) stains most epithelial-derived tissue, including liver, renal tubular epithelium, and hepatocellular and renal cell carcinomas. Anti-Cytokeratin (CAM 5.2) might not react with some squamous cell carcinomas.
Additional information
| Clone | CAM5.2 |
|---|---|
| Isotype | IgG2a |
| Immunogen | Anti-Cytokeratin, clone CAM 5.2, is derived from hybridization of mouse P3/NS-1/1-Ag4-1myeloma cells with spleen cells from BALB/c mice immunized with the human colorectal carcinoma cell line HT29. |
| Species | Mouse |
| Cellular Localization | Cytoplasmic |
| Positive Control Tissue | Colon, Lung, prostate and breast tissue. |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Conc Mouse Monoclonal Antibody |
| Format | Purified immunoglobulin |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Albers et al. Am J Pathol 90: 17, 1988.
- Ellis et al. J Clin Pathol 41: 1064, 1988. Oikawa et al. Biochem
- Biophys Res Commun 144: 634, 1987.
- Pfaltz et al. Virchows Arch A 411: 387, 1987.
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