Description
This antibody reacts with a protein of 60 kDa. E2Fs are DNAbinding proteins, which associate with negative regulators, such as the retinoblastoma p107 protein, resulting in an altered rate of gene transcription. E2F-1 is proposed to be involved in several cellular processes that range from tumor suppression, cell progression and oncogenesis. E2F-1 over expression can also drive cells into apoptosis.
Additional information
| Clone | KH95 |
|---|---|
| Isotype | IgG2a |
| Immunogen | BALB/C mice were immunized with a recombinant human E2F-1 protein. |
| Species | Mouse |
| Cellular Localization | Nuclear |
| Positive Control Tissue | Breast carcinoma, Tonsil |
| Pretreatment | EDTA Buffer pH 8.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD, RUO |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as an ascites fluid. It contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
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