Description
This antibody reacts with a 32 kDa protein. Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTL) and in natural killer (NK) cells. A number of granzymes (A to G) have been isolated and cloned. Human granzyme B isinvolved in target cell apoptosis during lymphocyte-mediated cytotoxicity. This antibody is useful in the localization of granzyme B containing lytic granules and for the characterization of activated CTL or NK cells.
Additional information
| Clone | Rabbit |
|---|---|
| Immunogen | A synthetic peptide from the N-terminus of human granzyme B. |
| Species | Rabbit |
| Cellular Localization | Cytoplasmic |
| Positive Control Tissue | Tonsil |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Rabbit Polyclonal Antibody |
| Format | Purified immunoglobulin fraction ofrabbit antiserum against Granzyme B containing sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
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