This antibody reacts with a 32 kDa protein. Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTL) and in natural killer (NK) cells. A number of granzymes (A to G) have been isolated and cloned. Human granzyme B isinvolved in target cell apoptosis during lymphocyte-mediated cytotoxicity. This antibody is useful in the localization of granzyme B containing lytic granules and for the characterization of activated CTL or NK cells.
A synthetic peptide from the N-terminus of human granzyme B.
|Positive Control Tissue
Citrate Buffer pH 6.0
|Incubation & Temperature
30 min @ RT
PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System
Rabbit Polyclonal Antibody
Purified immunoglobulin fraction ofrabbit antiserum against Granzyme B containing sodium azide as a preservative.
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