Description
This antibody is specific to a 70 kDa protein, which is a potent cytolytic poreforming protein. Perforin is a specific marker of functionally active cytotoxic T-lymphocytes and natural killer cells. Perforin mediates cytolysis of target cells by membrane damage and apoptosis.
Additional information
| Catalog No. | Mob555 Concentrated, PDM555 Prediluted |
|---|---|
| Clone | 5B10 |
| Isotype | IgG1 |
| Immunogen | Recombinant protein corresponding to an external region of the C-terminus of the perforin molecule |
| Species | Mouse |
| Cellular Localization | Cytoplasmic |
| Positive Control Tissue | Spleen |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as a tissue culture supernatant and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Hameed et al. Am 1 Pathol 140 (5): 1025, 1992.
- Lichtenheld MG et al. Nature 335: 448, 1988.
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