Description
The progesterone receptor (PgR) is an estrogen-regulated protein. It has been proposed that expression of PgR indicates a responsive estrogen receptor (ER) pathway.A number of studies have shown that PgR determination provides supplementary information to ER, both in predicting response to endocrine therapy and estimating survival. PgR has proved superior to ER as a prognostic indicator in some studies.
Additional information
| Catalog No. | RMAB002, RMAB002R – Concentrated, RMPD002, RMPD002R – Prediluted |
|---|---|
| Clone | SP2 |
| Isotype | Rabbit IgG |
| Immunogen | Recombinant protein encoding human progesterone receptor 412-526 aa. |
| Species | Rabbit |
| Cellular Localization | Nuclear |
| Positive Control Tissue | Breast carcinoma |
| Pretreatment | EDTA Buffer pH 8.0 (Manual/ Montage) |
| Incubation & Temperature | 30-60 min @ RT |
| Intended Use | IVD, RUO |
| Detection System | PolyVue™ Plus – Two Step Detection System or Montage PolyVue Plus™ Auto Detection System for Montage 360 System or HighLighter core kit for HighLighter Staining System |
| Description/Type | Rabbit Monoclonal Antibody |
| Format | Tissue Culture Supernatant |
DATASHEETS & SDS
REFERENCES
REFERENCES
- Cano, G., et. al. Estimation of Hormone Receptor Status in fineNeedle Aspirates and Paraffin-embedded sections from Breast Cancer Using the Novel Rabbit Monoclonal antibodies SP1 and SP2.Diagn Cytopathol, 2003 Oct 29(4):207-211.
- Huang Z., et al . Novel rabbit monoclonal antibody to progesterone receptor (Clone SP2): No heat pretreatment but effective on paraffinembedded tissue. Applied Immunohistochemistry and Molecular Morphology.
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