Description
This antibody is specific to 450 kDa (non-reduced) and 170 to 180 kD (reduced) form of thrombospondin. Thrombospondin is a protein from platelet α granules. It is secreted at sites of platelet activation and aggregation and is involved in the differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells.
Additional information
| Catalog No. | Mob315 Concentrated |
|---|---|
| Clone | A6.1 |
| Isotype | IgG1 |
| Immunogen | BALB/C mice were injected with reduced and alkylated purified human TSP (fully denatured) from the supernatant of thrombin-activated platelets. |
| Species | Mouse |
| Cellular Localization | endoplasmic reticulum, Golgi complex, Secretory granules |
| Positive Control Tissue | Tonsil |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Conc Mouse Monoclonal Antibody |
| Format | This product is supplied as a purified immunoglobulin and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet |
REFERENCES
REFERENCES
- Dixit et al. Biochemistry 24 (16): 4270, 1985.
- Dixit et al. J Bio Chem 261 (4): 1962, 1986.
- Galvin et al. J Cell Bio 104 (5): 1413, 1987.
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