Description
Cytokeratin 20 represents an excellent marker for certain types of carcinomas such as adenocarcinomas of the colon, transitional cell carcinomas of the bladder andMerkel cell tumors of the skin. Very sensitive detection of intestinal and gastric foveolar epithelium, urothelial umbrella cells, Merkel cells of the epidermis as well as tumors originating therefrom (e.g. primary and metastatic colorectal carcinoma). Adenocarcinomas of breast, lung, endometrium, and ovary (non-mucinous) as well as neuroendocrine tumors of the lung are essentially negative
Additional information
| Clone | Ks20.8 |
|---|---|
| Isotype | IgG2a, kappa |
| Immunogen | Cytokeratins isolated from human microdissected villi of human duodenal mucosa. |
| Species | Mouse |
| Cellular Localization | Cytoplasmic |
| Positive Control Tissue | Colon carcinoma, skin |
| Pretreatment | HistoZyme |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue™ Plus – Two Step Detection Systemor Montage PolyVue Plus™ Auto Detection System forMontage 360 Systemor HighLighter core kit for HighLighter Staining System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | This product is supplied as a culture supernatant and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Moll, R., et al., 1990, J. Cell Biol. 111, 567-580.
- Moll, R., et al., 1992, Am. K. Path. 140, 427-447.
- Moll, I., et al., 1991, Arch. Dermatol. Res. 283, 300-309.
- Moll, R., et al., 1993, Differentiation 53, 75-93.
- Mobus V.J. et al., 1994, Br. J. Cancer 69, 422-428.
- Denirkesen C. et al., 1995, J. Cutan Pathol. 2, 518-535.
- Chinxiao Z. et al., 1996, Differentiation 61,121-127.
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