The mammaglobin gene was first identified using a differential screening approach directed at the isolation of novel, human breast cancer-associated genes. Mammaglobin-A is highly overexpressed in breast cancer cell lines and primary breast tumors. This pattern of expression is restricted to mammary epithelium and metastatic breast tumors. Thus, mammaglobin-Aspecific T cell immune responses may provide an important approach for the design of breast cancer-specific immunotherapy.
Mammaglobin A
Catalog No: RMAB036-
Categories: Primary Antibodies, IVD - For U.S. Market, IVD - Outside U.S. Market
Tags: Concentrated, M
Description
Additional information
| Catalog No. | RMAB036 Concentrated, RMPD036 Prediluted |
|---|---|
| Clone | EPR 9092 |
| Isotype | Rabbit IgG |
| Immunogen | A recombinant protein fragment corresponding to human Mammaglobin A. |
| Species | Rabbit |
| Cellular Localization | Cytoplasmic |
| Positive Control Tissue | Breast carcinoma |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Rabbit Monoclonal Antibody |
| Format | This product is supplied as a tissue culture supernatant and contains sodium azide as a preservative. |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Span PN et al. J Clin Oncol 22(4):691-8, 2004
- Jaramillo A et al. Int J Cancer 102(5):499-506, 2002
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