PCNA is essential for cellular DNA synthesis. This antibody reacts with proliferating cells in a wide range of normal tissues. The significance of PCNA immunoreactivity in tumors in not fully established. However, in non-Hodgkin lymphoma a linear relation between Ki-67 and PCNA staining has been demonstrated.
Proliferating Cell Nuclear Antigen (PCNA) (PC10)
Catalog No: 8512
Categories: Primary Antibodies, IVD - For U.S. Market, IVD - Outside U.S. Market
Tags: Highlighter Product, HL72K-Core Kit, Concentrated, P
Description
Additional information
| Catalog No. | Mob083 Concentrated, PDM014 Prediluted |
|---|---|
| Clone | PC10 |
| Isotype | IgG2a, kappa |
| Immunogen | Rat PCNA made in the protein A expression vector pR1T2T. |
| Species | Mouse |
| Cellular Localization | Nuclear |
| Positive Control Tissue | Breast carcinoma, Tonsil |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue™ Plus – Two Step Detection System or Montage PolyVue Plus™ Auto Detection System for Montage 360 System or HighLighter core kit for HighLighter Staining System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | Purified immunoglobulin |
DATASHEETS & SDS
DATASHEETS & SDS
| Download Datasheet |
| Download SDS Sheet – OSHA |
REFERENCES
REFERENCES
- Waseem et al. J Cell Sci 96: 121, 1990.
- Takasaki et al. J Exp Med159: 981, 1984.
- Hall et al. J Pathol 162: 285, 1990.
- Coltreraet al. Applied Immunohistochemistry 1: 193, 1993
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